After installing the pre-requisites and installing Exchange, when connecting to the exchange server using the Exchange Management Shell you may receive an error similar to the following.
“The WS-Management service does not support the request. For more information, see the about_Remote_Troubleshooting Help Topic”
It appears that the setup routine may not always register the .NET framework on IIS, so to get this to work you need to register .NET Framework 4 on IIS manually. To do this run the following command from an administrative command prompt.
%SystemDrive%\Windows\Microsoft.NET\Framework64\v4.0.30319\aspnet_regiis.exe -ir -enable
then restart IIS, this should solve the problem.
The Microsoft Cloud Blog 
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